IN VITRO FERTILIZATION (IVF) / ICSI

Our ART (Artificial Reproductive Technique) program was incepted in the year 2002 with the pioneers of  IVF work in India, Dr. Jatin Shah and leading embryologist Sudesh Kamath. Since then, we have achieved upward of 300 live births, with a steady success rate of 38% which is on par with world standards.

CYCLES
IVF BABIES
%
SUCCESS RATE

WHAT IS IVF?

In Vitro Fertilization literally means fertilization (formation of embryo) that occurs outside the body. The egg and sperm are collected, fertilized and incubated outside the body, and the resultant embryo is then introduced into the uterus. It is carried out in a setup with a specific micro environment with controlled pH, Temperature and Humidity, within a Co2 incubator in order to mimic a uterine environment outside the body. The basic steps involved in IVF / ICSI are listed below.

Ovarian Stimulation - IVF

I. OVARIAN STIMULATION

Medication is given to the patient in order to stimulate multiple egg development. The growth of the egg is monitored by ultrasound.

Egg Collection - IVF

II. EGG COLLECTION

Also known as Oocyte Pickup, the eggs produced by the female partner are collected.

Semen Preparation - IVF

III. SEMEN PREPARATION

The semen from the male partner is collected, screened and prepared for optimal chances of fertilization. 

Fertilization - IVF

IV. FERTILIZATION

Fertilization is then accomplished through IVF (in which the sperm and egg are layered together in a medium) or through ICSI (in which the sperm is introduced into the egg). The choice of procedure depends on the patient profile.

Incubation - IVF

V. INCUBATION

The fertilized egg is stored in a culture medium within an incubator, in which the external parameters (temperature, pH, humidity) are controlled to mimic a uterine environment.

Embryo Transfer - IVF

VI. EMBRYO TRANSFER

The developed embryo is transferred from the incubator and introduced into the uterine cavity to achieve pregnancy.

FACTORS INDICATING THE NEED FOR IVF

Initially, IVF was done for Tubal Factor Infertility, when the Fallopian tubes were diseased, blocked or damaged. Since the tubes are the site of fertilization, it becomes impossible for the embryo to form successfully.  

With continuous development, the IVF process has expanded to handle cases of infertility which failed to conceive by preliminary treatment options. 

  • Ovulatory Dysfunction (PCOS, Anovulation, Oligovulation)
  • Male Factor Infertility (TESA / PESA for azoospermia)
  • Endometriosis
  • Tubal Factor
  • Failed COH & IUI
  • Elderly Age Groups (nearing 40 years)
  • Egg Donation Programs (Premature Ovarian Failure)
  • Embryo Donation Programs

OUTLINE OF OUR ART PROGRAM

Our ART program includes a series of steps, inclusive of pre and post procedural services, to ensure that the patient is well equipped, physically and mentally, to undergo this procedure. Overall, the program covers a period of 2 – 3 weeks.

Both partners undergo detailed investigation and infertility work ups to assess the ovulatory status, uterine cavity (for implantation) and male factor. They will be started on pre IVF treatments which includes medication to improve egg production, sperm quality and motility. Uterine factors are corrected surgically (if needed). 

Both partners will undergo detailed IVF counseling sessions, where the procedure will be explained with details of cost and success ratios.

Down regulation, a medication regime that prepares the body for the ART procedure, will begin 10 – 15 days prior to stimulation which is the beginning of the IVF process.

Ovarian Stimulation begins with individualized patient tailored regimes and doses adjusted by hormone essays and Trans Vaginal Scans (TVS) to track the follicular development at regular intervals.

Oocyte Pick up (OPU) will be scheduled as a short anesthetic procedure, approximately 35 hours post trigger.

 The fertiliazation is accomplished by either IVF (In Vitro Fertilization) or ICSI (Intra Cytoplasmic Sperm Injection) depending on the patient profile at that point.

Embryos will be cultured in protein enhanced culture mediums in Co2 incubators. They will be graded and transferred to the uterine cavity on day 2 / day 3 and the excess embryos will be frozen for future need, if any. 

Luteal support medication is given for 15 days after which pregnancy is confirmed by serum beta HCG test.

OUR IVF SPECIALIST TEAM

Our ART program is done with a specialist team, comprising of experts in various reproductive fields, including one of the leading embryologists in the country.

Embryologist

SUDESH KAMAT

M Sc. Applied Biology DMLT, Consultant Reproductive Biologist

In the team of first successful pregnancy by means of: 
ICSI (1994), MESA (1996), Assisted Hatching by PZD (1996) and in the case of Immotile Celia Syndrome (1996).

He has presented many research publications in National & International journals and conferences and achieved numerous pregnancies through ICSI  in India and abroad, achieving 40 – 50 precent success rates (on par with world standards)

Embryologist

DR. S. SUMATHI

MD DGO, IVF Specialist

Completed IVF Training in NUH, Singapore and started this ART Program in 2002, the first of its kind in North Chennai.

She has worked alongside renowned IVF specialists such as Dr. Jatin Shah and Dr. Sanjay Patel.

Embryologist

SEEMA NAIR

M Sc. Applied Biology DMLT, Consultant Reproductive Biologist

With eight years of experience, she has worked as an embryologist in various IVF centers around the world.

 

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